Features
Composed of a double-layer hydrophilic Polyestersulfone (PES) media
Efficient mycoplasma, bacteria and particulate retention
Extensive chemical compatibility (pH 1-14)
Low extractables
Applications
Sterilize filtration of cell culture medium
Pre-column/ultra-filtration protection
Filtration of intermediate products/stock solutions
Filtration of blood products/serums
Sterile filtration of terminal products
Operating Conditions
| Max. Temperature | 80°C |
Max. Differential Pressure | 0.55 MPa / 25°C |
Materials of Construction
| Filter Type | Bricap C/D/L/T | Cartridge |
Membrane | Hydrophilic Polyethersulfone (PES) | Hydrophilic Polyethersulfone (PES) |
| Core/Cage/End Cap | Polypropylene (PP) | Polypropylene (PP) |
Capsule Shell | Polypropylene (PP) | - |
| O-ring | - | Silicone/EPDM/ Viton/PTFE |
Capsule Vent O-ring | Silicone | - |
| Removal Ratings | 0.2+0.1 μm / 0.45+ 0.1 μm | |
Biological Safety
Bio-compatibility | Meet the requirement of USP<87>In Vitro Cytotoxicity Test; Meet the criteria of the USP<88>Biological Reactivity Test for Class VI-121°C plastics |
| Endotoxins | < 0.25 EU/ml |
Effective Filtration Area
| BriScale A50 | Bricap C | Bricap L | Bricap T | Cartridge |
A50: 20 cm2 | C01: 180 cm2 | L02: 0.12 m2 | T10: 0.55 m2 | 5" : 0.28m2 |
| C02: 420 cm2 | L03: 0.16 m2 | T20: 1.1 m2 | 10": 0.55m2 | |
C03: 660 cm2 | L05: 0.28 m2 | T30: 1.65 m2 | 20": 1.1m2 | |
| D01: 350 cm2 | L10: 0.55 m2 | 30": 1.65m2 | ||
L20: 1.1 m2 | 40": 2.2m2 | |||
| L30: 1.65 m2 |
Sterilization Capability
| Sterilization Method/Filter Format | BriScale Disc, Bricale C/ L / T | Bricap D | Cartridge |
Gamma-irradiation | 25-45 Kgy | / | / |
Autoclave (126°C) applies only to Gamma-compatible package | 5 cycle, 30min | / | / |
Autoclave (130°C) applies only to Atoclave package | 25 cycle, 30min | 25 cycle, 30min | 25 cycle, 30min |
| SIP (135°C) applies only to cartridge | / | / | 25 cycle, 30min |
COPYRIGHT 2014 Hangzhou Cobetter Filtration Equipment Co.,Ltd ALL RIGHTS RESERVED.
